Halobacterium salinarum NRC-1
Environmental and Gene Regulatory Influence Network (EGRIN)
Bonneau, R., M. T. Facciotti, D. J. Reiss, A. K. Schmid, M. Pan, A. Kaur, V. Thorsson, P. Shannon, M. H. Johnson, J. C. Bare, W. Longabaugh, M. Vuthoori, K. Whitehead, A. Madar, L. Suzuki, T. Mori, D. E. Chang, J. Diruggiero, C. H. Johnson, L. Hood & N. S. Baliga, (2007) A predictive model for transcriptional control of physiology in a free living cell. Cell 131: 1354-1365.
Run #2 (2010, Kaur, Baliga, et al)Amardeep Kaur, Phu T. Van, Courtney R. Busch, Courtney K. Robinson, Min Pan, Wyming Lee Pang, David Reiss, Jocelyne DiRuggiero, and Nitin S. Baliga, (2010) Coordination of frontline defense mechanisms under severe oxidative stress. Molecular Systems Biology in press
EGRIN enables searching a database of gene/condition biclusters in the organism Halobacterium sp. NRC-1. A bicluster is a set of genes whose expression behaves coherently under a set of conditions. For each bicluster, EGRIN displays a list of genes and regulators, a regulatory circuit diagram, and a PDF containing supporting information for clustering.
Clusters were identified by the cMonkey algorithm and regulatory circuits were computed by Inferelator. Circuit diagrams created by BioTapestry.
Using the VNG naming system, search for genes that belong to or regulate biclusters. Regulators may be genes or environmental factors (for example: oxygen, illumination, gamma, cu, fe...). In addition, searching all fields will also search based on functional annotations, motif sequence (exact match only), or cluster ID.
