| This system is for research purposes and is not meant to be used by clinical service providers in the course of treating patients. |
This page describes a relationship from the Multiomics KG knowledge graph version 2.1.0 |
| Background | The Multiomics KG, created and maintained by the Multiomics Provider, provides knowledge collected from the supplementary tables from many published multiomics papers. Relationships ('edges') in this knowledge graph represent associations between metabolites, gene expression levels, clinical observations, diseases, etc.
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| Description | This relationship represents the finding that ACM1_HUMAN Muscarinic acetylcholine receptor M1 (sprot) is positively associated with irritable bowel syndrome.
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| Supporting evidence | The strength of the association (Linear regression) is 0.0017, with p-value of 0.046, as observed among N = 54219 individuals.
Method notes: Proteomic associations with smoking, medication use, liver function, renal function and top 20 most prevalant diseases.
This relationship was reported in ST7 (row 1750) of Sun 2023.
File caption: Supplementary Tables 1–30 and the table legends.
In the source file, the subject is called "CHRM1:P11229:OID30930:v1". This is was interpreted as a synonym for ACM1_HUMAN Muscarinic acetylcholine receptor M1 (sprot) (UniProtKB:P11229).
In the source file, the object is called "Irritable bowel syndrome".
This relationship was curated by Skye Lane Goetz, Institute for Systems Biology.
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| The assertion is:
correctly interpreted
useful
Create new github issue |